Depression and interferon-alpha therapy
نویسندگان
چکیده
منابع مشابه
EFFICACY AND SAFETY OF COMBINATION THERAPY OF INTERFERON-ALPHA 2B PLUS RIBAVIRIN FOR CHRONIC HEPATITIS C
Introduction: The aim of this study is to assess the therapeutic efficacy and safety of a particular brand of IFN alpha (PDferon B®) in combination with ribavirin (RlBA) on Iranian patients with chronic hepatitis C (CHC). The addition of RIBA to the standard treatment with interferon (IFN) alpha led to an improvement in sustained virologic response (SVR) from less than 20% with IFN monother...
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Five patients with multiple, recurrent conjunctival papillomas underwent surgical excision of their tumor and then received interferon alpha-N1, 5 X 10(6) units/m2 (5 Mu/m2), intramuscularly daily for one month. A similar dose was given two to three times per week for the next six months and tapered off or discontinued thereafter. The follow-up period varied from one to four years. Two patients...
متن کاملProbable involvement of p11 with interferon alpha induced depression.
Depression is one of the major side effects of interferon alpha (IFN-α) treatment, but the molecular mechanism underlying IFN-α-induced depression remains unclear. Several studies have shown that the serotonin receptors 5-HTR1b and 5-HTR4 play key roles in the anti-depression effects associated with p11 (S100A10). We investigated the effects of IFN-α on the regulation of p11, 5-HTR1b and 5-HTR4...
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Chronic infection with the hepatitis C virus is a common and growing problem, often affecting persons with psychiatric and substance use problems. Neuropsychiatric symptoms are commonly associated with chronic hepatitis C virus infection, its sequelae, and its treatment. Interferon-alpha (IFN-alpha) treatment has been repeatedly shown to induce significant symptoms of depression in 20% to 50% o...
متن کاملinterferon alpha-2b therapy in chronic hepatitis delta
results overall, 3 (15%) subjects achieved svr, 10 cases (50%) relapsed after treatment cessation and 7 (35%) patients did not clear hdv during the treatment. conclusions hdv coinfection with hbv had very low response rate to high doses and long durations of ifn α-2b therapy. objectives we aimed to determine the efficacy of ifn α-2b therapy in patients with hbv/hdv coinfection. patients and met...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2000
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.176.5.494-a